Publications from Protein Biology Group

Total publications from unit:

2019

1.

Lau D Nielsen, Mads M Foged, Anastasia Albert, Andreas B Bertelsen, Cecilie L Søltoft, Samuel D Robinson, Steen V Petersen, Anthony W Purcell, Baldomero M Olivera, Raymond S Norton, Terje Vasskog, Helena Safavi-Hemami, Kaare Teilum and Lars Ellgaard. (2019) The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework The Journal of Biological Chemistry 286(2):308-10.

2.

Michael Lückmann, Mette Trauelsen, Marie A Bentsen, Tinne A D Nissen, Joao Martins, Zohreh Fallah, Mads M Nygaard, Elena Papaleo, Kresten Lindorff-Larsen, Thue W Schwartz and Thomas M Frimurer. (2019) Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1 Proceedings of the National Academy of Sciences of the United States of America 116(14):7123-7128.

3.

Amelie Stein, Douglas M. Fowler, Rasmus Hartmann-Petersen and Kresten Lindorff-Larsen. (2019) Biophysical and Mechanistic Models for Disease-Causing Protein Variants Trends in Biochemical Sciences 35(25):1-14.

4.

Lene Clausen, Amanda Bering Abildgaard, Sarah K. Gersing, Amelie Stein, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2019) Protein stability and degradation in health and disease Molecular Chaperones in Human Disorders 40(4):444-457.

5.

Niels Hadrup, Kristina Bram Knudsen, Trine Berthing, Henrik Wolff, Stefan Bengtson, Christian Kofoed, Roall Espersen, Casper Højgaard, Jakob Rahr Winther, Martin Willemoës, Irene Wedin, Markus Nuopponen, Harri Alenius, Hannu Norppa, Håkan Wallin and Ulla Vogel. (2019) Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses Environmental Toxicology and Pharmacology 66(2):116-125.

6.

Rasmus Scheller, Amelie Stein, Sofie V. Nielsen, Frederikke I. Marin, Anne-Marie Gerdes, Miriam Di Marco, Elena Papaleo, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2019) Toward mechanistic models for genotype-phenotype correlations in phenylketonuria using protein stability calculations Human Mutation 40(4):444-457.

7.

Sandro Bottaro, Giovanni Bussi, Giovanni Pinamonti, Sabine Reisser, Wouter Boomsma and Kresten Lindorff-Larsen. (2019) Barnaba RNA 25(2):219-231.

2018

8.

Joao Henriques, Lise Arleth, Kresten Lindorff-Larsen and Marie Skepo. (2018) On the Calculation of SAXS Profiles of Folded and Intrinsically Disordered Proteins from Computer Simulations Journal of Molecular Biology 430:2521-2539.

9.

Tone Bengtsen, Viktor Lindahl Holm, Søren Roi Midtgaard, Lise Arleth and Kresten Lindorff-Larsen. (2018) A Combined Simulation and SAXS Study of the Dynamics of Lipid Nanodiscs Biophysical Journal 114:559A-559A.

10.

Lars Ellgaard, Carolyn S. Sevier and Neil J. Bulleid. (2018) How are proteins reduced in the endoplasmic reticulum? Trends in Biochemical Sciences 43(1):32-43.

11.

Line V. Kristensen, Felix S. Oppermann, Matthias J. Rauen, Karina Fog, Thorsten Schmidt, Jana Schmidt, Tina Harmuth, Rasmus Hartmann-Petersen and Kenneth Thirstrup. (2018) Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function Neurochemistry International 112(4):5-17.

12.

Birte Hoecker and Jakob R. Winther. (2018) Editorial overview: A perspective on protein evolution Current Opinion in Structural Biology 48(11):viii-ix.

13.

Casper Højgaard, Henrik Vinther Sørensen, Jan Skov Pedersen, Jakob Rahr Winther and Daniel Erik Otzen. (2018) Can a Charged Surfactant Unfold an Uncharged Protein? Biophysical Journal 115(11):2081-2086.

14.

Elena Papaleo, Carlo Camilloni, Kaare Teilum, Michele Vendruscolo and Kresten Lindorff-Larsen. (2018) Molecular dynamics ensemble refinement of the heterogeneous native state of NCBD using chemical shifts and NOEs PeerJ 6(5):1-24.

15.

Helena Safavi-Hemami, Mads Møller Foged and Lars Ellgaard. (2018) Evolutionary Adaptations to Cysteine-rich Peptide Folding Oxidative Folding of Proteins 43(1):32-43.

16.

Henrik O'Brien, Shingo Kanemura, Masaki Okumura, Robert P. Baskin, Pradip K. Bandyopadhyay, Baldomero M. Olivera, Lars Ellgaard, Kenji Inaba and Helena Safavi-Hemami. (2018) Ero1-Mediated Reoxidation of Protein Disulfide Isomerase Accelerates the Folding of Cone Snail Toxins International Journal of Molecular Sciences 19(11):1-15.

17.

Jill J. Bouchard, Joel H. Otero, Daniel C. Scott, Elzbieta Szulc, Erik W. Martin, Nafiseh Sabri, Daniele Granata, Melissa R. Marzahn, Kresten Lindorff-Larsen, Xavier Salvatella, Brenda A. Schulman and Tanja Mittag. (2018) Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments Molecular Cell 72(1):19-36, e1-e8.

18.

Katharina Weinhaupl, Caroline Lindau, Audrey Hessel, Yong Wang, Conny Schültze, Tobias Jores, Laura Melchionda, Birgit Schönfisch, Hubert Kalbacher, Beate Bersch, Doron Rapaport, Martha Brennich, Kresten Lindorff-Larsen, Nils Wiedemann and Paul Schanda. (2018) Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space Cell 175(5):1365-1379, e25.

19.

Katrine Østergaard Bugge, Lasse Staby, Katherine Rosemary Kemplen, Charlotte O'Shea, Sidsel Krogh Bendsen, Mikael Kryger Jensen, Johan Gotthardt Olsen, Karen Skriver and Birthe Brandt Kragelund. (2018) Structure of radical-induced cell death1 hub domain reveals a common aa-scaffold for disorder in transcriptional networks Structure 26(5):734-746.

20.

Kristoffer Enøe Johansson and Jakob R. Winther. (2018) Protein evolution Nature Chemical Biology 14(3):202-204.

21.

Maher M. Kassem, Lars B. Christoffersen, Andrea Cavalli and Kresten Lindorff-Larsen. (2018) Enhancing coevolution-based contact prediction by imposing structural self-consistency of the contacts Scientific Reports 8(5):74-82.

22.

Manoj K. Singh, Sandra Richter, Hauke Beckmann, Marika Kientz, York-Dieter Stierhof, Nadine Anders, Florian Fäßler, Michael Nielsen, Christian Knöll, Alexis Thomann, Mirita Franz-Wachtel, Boris Macek, Karen Skriver, Peter Pimpl and Gerd Jürgens. (2018) A single class of ARF GTPase activated by several pathway-specific ARF-GEFs regulates essential membrane traffic in Arabidopsis PLoS Genetics 14(11):1-36.

23.

Maria Louise Mønster Jørgensen, Babatunde Ekundayo, Mikel Zaratiegui, Karen Skriver, Genevieve Thon and Thomas Schalch. (2018) Structure of the replication regulator Sap1 reveals functionally important interfaces Scientific Reports 8(5):734-746.

24.

Marit Ilves, Sara Vilske, Kukka Aimonen, Hanna K. Lindberg, Saila Pesonen, Irene Wedin, Markus Nuopponen, Esa Vanhala, Casper Højgaard, Jakob R. Winther, Martin Willemoës, Ulla Vogel, Henrik Wolff, Hannu Norppa, Kai Savolainen and Harri Alenius. (2018) Nanofibrillated cellulose causes acute pulmonary inflammation that subsides within a month Nanotoxicology 12(7):729-746.

25.

Mustapha Carab Hussein Ahmed, Elena Papaleo and Kresten Lindorff-Larsen. (2018) How well do force fields capture the strength of salt bridges in proteins? PeerJ 6(1):19-36, e1-e8.

26.

Paul Santner, Joao Miguel da Silva Martins, Caroline Kampmeyer, Rasmus Hartmann-Petersen, Jonas S. Laursen, Amelie Stein, Christian A Olsen, Isaiah T Arkin, Jakob R. Winther, Martin Willemoës and Kresten Lindorff-Larsen. (2018) Random mutagenesis analysis of the Influenza A M2 proton channel reveals novel resistance mutants Biochemistry 57(41):5957-5968.

27.

Paul Santner, João Miguel da Silva Martins, Jonas S. Laursen, Lars Behrendt, Leise Riber, Christian A Olsen, Isaiah T. Arkin, Jakob R. Winther, Martin Willemoës and Kresten Lindorff-Larsen. (2018) A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel Biochemistry 57(41):5949-5956.

28.

Robert B. Best and Kresten Lindorff-Larsen. (2018) Editorial overview: Theory and simulation: Interpreting experimental data at the molecular level Current Opinion in Structural Biology 49(5):iv-v.

29.

Sandro Bottaro and Kresten Lindorff-Larsen. (2018) Biophysical experiments and biomolecular simulations Science 361(6400):355-360.

30.

Sandro Bottaro, Giovanni Bussi, Scott D. Kennedy, Douglas H. Turner and Kresten Lindorff-Larsen. (2018) Conformational ensembles of RNA oligonucleotides from integrating NMR and molecular simulations Science Advances 4(5):19-36, e1-e8.

31.

Signe Marie Schenstrøm, Caio A. Rebula, Michael H. Tatham, Ruth Hendus-Altenburger, Isabelle Jourdain, Ronald T. Hay, Birthe B. Kragelund and Rasmus Hartmann-Petersen. (2018) Expanded Interactome of the Intrinsically Disordered Protein Dss1 Cell Reports 25(4):862-870.

32.

Yong Wang, Katrine Østergaard Bugge, Birthe Brandt Kragelund and Kresten Lindorff-Larsen. (2018) Role of protein dynamics in transmembrane receptor signalling Current Opinion in Structural Biology 48(5):74-82.

33.

Yong Wang, Omar Valsson, Pratyush Tiwary, Michele Parrinello and Kresten Lindorff-Larsen. (2018) Frequency adaptive metadynamics for the calculation of rare-event kinetics Journal of Chemical Physics 149(7):1-7.

2017

34.

Caroline Kampmeyer, Sofie V. Nielsen, Lene Clausen, Amelie Stein, Anne-Marie Axø Gerdes, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2017) Blocking protein quality control to counter hereditary cancers Genes, Chromosomes & Cancer 56(12):823-831.

35.

Alise J. Ponsero, Aeid Igbaria, Maxwell A. Darch, Samia Miled, Caryn E. Outten, Jakob R. Winther, Gael Palais, Benoit D'Autréaux, Agnès Delaunay-Moisan and Michel B. Toledano. (2017) Endoplasmic reticulum transport of glutathione by Sec61 is regulated by Ero1 and Bip Molecular Cell 67(6):962-973.e5.

36.

Caroline Kampmeyer, Antonina Karakostova, Signe Marie Schenstrøm, Amanda B. Abildgaard, Anne Marie Lauridsen, Isabelle Jourdain and Rasmus Hartmann-Petersen. (2017) The exocyst subunit Sec3 is regulated by a protein quality control pathway Journal of Biological Chemistry 292(37):15240-15253.

37.

Ruth Hendus-Altenburger, Matteo Lambrughi, Thilde Bagger Terkelsen, Stine Helene Falsig Pedersen, Elena Papaleo, Kresten Lindorff-Larsen and Birthe Brandt Kragelund. (2017) A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins - Lessons from the sodium proton exchanger 1 (NHE1) Cellular Signalling 37(9):40-51.

38.

Yong Wang, João Martins and Kresten Lindorff-Larsen. (2017) Biomolecular conformational changes and ligand binding Chemical Science 8(9):6466-6473.

39.

Farah Deeba, Tasawar Sultana, Tariq Mahmood, Charlotte O'Shea, Karen Skriver and S. M. Saqlan Naqvi. (2017) Involvement of WRKY, MYB and DOF DNA-binding proteins in interaction with a rice germin-like protein gene promoter Acta Physiologiae Plantarum 39(11):1-36.

40.

Mads Nygaard, Birthe Brandt Kragelund, Elena Papaleo and Kresten Lindorff-Larsen. (2017) An efficient method for estimating the hydrodynamic radius of disordered protein conformations Biophysical Journal 113(3):550-557.

41.

Lasse Staby, Charlotte O'Shea, Martin Willemoës, Frederik Theisen, Birthe Brandt Kragelund and Karen Skriver. (2017) Eukaryotic transcription factors Biochemical Journal 474(15):2509-2532.

42.

Sandro Bottaro and Kresten Lindorff-Larsen. (2017) Mapping the universe of RNA tetraloop folds Biophysical Journal 113(2):257-267.

43.

E.C. dos Santos, Z. Rozynek, E.L. Hansen, Rasmus Hartmann-Petersen, R.N. Klitgaard, Anders Løbner-Olesen, L. Michels, A. Mikkelsen, Heloisa Nunes Bordallo and J.O. Fossum. (2017) Ciprofloxacin intercalated in fluorohectorite clay R S C Advances 7(43):26537-26545.

44.

Line V. Kristensen, Felix S. Oppermann, Matthias J. Rauen, Rasmus Hartmann-Petersen and Kenneth Thirstrup. (2017) Polyglutamine expansion of ataxin-3 alters its degree of ubiquitination and phosphorylation at specific sites Neurochemistry International 105(43):42-50.

45.

Sirke Virkkunen, Henrik Wolff, Caj Haglund, Casper Højgaard, Jakob R. Winther, Martin Willemoës, Ulla Vogel and Jaana Hagström. (2017) Positive staining for cellulose in oral pulse granuloma Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 123(4):464-467.

46.

Sofie V, Nielsen, Amelie Stein, Alexander B. Dinitzen, Elena Papaleo, Michael H. Tatham, Esben Guldahl Poulsen, Maher Mahmoud Kassem, Lene Juel Rasmussen, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen. (2017) Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations PLoS Genetics 13(4):42-50.

47.

Bjarne Hove-Jensen, Kasper R. Andersen, Mogens Kilstrup, Jan Martinussen, Robert L. Switzer and Martin Willemoës. (2017) Phosphoribosyl diphosphate (PRPP) Microbiology and Molecular Biology Reviews 81(1):464-467.

48.

Thu Phuong Tran, Christian Ørnbøl Larsen, Tobias Røndbjerg, Martina de Foresta, Micha Ben Achim Kunze, Ales Marek, Jacob Hartvig Løper, Lotte-Emilie Boyhus, Astrid Knuhtsen, Kresten Lindorff-Larsen and Daniel Sejer Pedersen. (2017) Diversity-oriented peptide stapling Chemistry: A European Journal 23(14):3490-3495.

49.

Tina Mostrup Kousted, Otto Kalliokoski, Sofie Kjellerup Christensen, Jakob R. Winther and Jann Hau. (2017) Exploring the antigenic response to multiplexed immunizations in a chicken model of antibody production Heliyon 3(3):464-467.

50.

Meng S. Choy, Yang Li, Luciana E. S. F. Machado, Micha Ben Achim Kunze, Christopher R. Connors, Xingyu Wei, Kresten Lindorff-Larsen, Rebecca Page and Wolfgang Peti. (2017) Conformational rigidity and protein dynamics at distinct timescales regulate PTP1B activity and allostery Molecular Cell 65(4):644-658.

51.

Charlotte O'Shea, Lasse Staby, Sidsel Krogh Bendsen, Frederik Grønbæk Tidemand, Andreas Redsted, Martin Willemoës, Birthe Brandt Kragelund and Karen Skriver. (2017) Structures and short linear motif of disordered transcription factor regions provide clues to the interactome of the cellular hub radical-induced cell death1 Journal of Biological Chemistry 292(2):512-527.

52.

Esben Guldahl Poulsen, Caroline Kampmeyer, Franziska Kriegenburg, Jens Vilstrup Johansen, Kay Hofmann, Christian Holmberg and Rasmus Hartmann-Petersen. (2017) UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1 Cell Stress & Chaperones 22(1):143-154.

53.

Julia Catalán, Elina Rydman, Kukka Aimonen, Kati-Susanna Hannukainen, Satu Suhonen, Esa Vanhala, Carlos Moreno, Valérie Meyer, Denilson da Silva Perez, Asko Sneck, Ulla Forsström, Casper Højgaard, Martin Willemoës, Jacob R. Winther, Ulla Vogel, Henrik Wolff, Harri Alenius, Kai M. Savolainen and Hannu Norppa. (2017) Genotoxic and inflammatory effects of nanofibrillated cellulose in murine lungs Mutagenesis 32(1):23-31.

54.

Helena Steinocher, Katrine Østergaard Bugge, Louise Fletcher Nikolajsen, Kresten Lindorff-Larsen, Andrew Brooks and Birthe Brandt Kragelund. (2017) Class I Cytokine Receptors Biophysical Society. Annual Meeting. Abstracts 112:171A.

2016

55.

Katrine Østergaard Bugge, Kresten Lindorff-Larsen and Birthe Brandt Kragelund. (2016) Understanding single-pass transmembrane receptor signaling from a structural viewpoint—what are we missing? The F E B S Journal 283(24):4424-4451.

56.

Lars Ellgaard, Nicholas McCaul, Anna Chatsisvili and Ineke Braakman. (2016) Co- and post-translational protein folding in the ER Traffic (Malden) 17(6):615-638.

57.

Birthe Brandt Kragelund, Eric Weterings, Rasmus Hartmann-Petersen and Guido Keijzers. (2016) The Ku70/80 ring in Non-Homologous End-Joining Frontiers in Bioscience 21(3):514-527.

58.

Birthe Brandt Kragelund, Signe Marie Schenstrøm, Caio A. Rebula, Vikram Govind Panse and Rasmus Hartmann-Petersen. (2016) DSS1/Sem1, a multifunctional and intrinsically disordered protein Trends in Biochemical Sciences 41(5):446-459.

59.

Casper Højgaard, Christian Kofoed, Roall Espersen, Kristoffer Enøe Johansson, Mara Villa, Martin Willemoës, Kresten Lindorff-Larsen, Kaare Teilum and Jakob R. Winther. (2016) A soluble, folded protein without charged amino acid residues Biochemistry 55(28):3949–3956.

60.

Ditte H. Welner, Farah Deeba, Leila Lo Leggio and Karen Skriver. (2016) NAC transcription factors Plant transcription factors 67(17):5259-5273.

61.

Esben Guldahl Poulsen, Sofie V. Nielsen, Elin J. Pietras, Jens Vilstrup Johansen, Cornelia Steinhauer and Rasmus Hartmann-Petersen. (2016) High-throughput siRNA screening applied to the ubiquitin-proteasome system Proteostasis 4(3):514-527.

62.

Helena Safavi-Hemami, Qing Li, Ronneshia L. Jackson, Albert S. Song, Wouter Krogh Boomsma, Pradip K. Bandyopadhyay, Christian W. Gruber, Anthony W. Purcell, Mark Yandell, Baldomero M. Olivera and Lars Ellgaard. (2016) Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides Proceedings of the National Academy of Sciences of the United States of America 113(12):3227-3232.

63.

Katrine Østergaard Bugge, Elena Papaleo, Gitte Wolfsberg Haxholm, Jonathan T.S. Hopper, Carol V. Robinson, Johan Gotthardt Olsen, Kresten Lindorff-Larsen and Birthe Brandt Kragelund. (2016) A combined computational and structural model of the full-length human prolactin receptor Nature Communications 7(21):4361-4377.

64.

Kresten Lindorff-Larsen, Paul Maragakis, Stefano Piana and David E Shaw. (2016) Picosecond to Millisecond Structural Dynamics in Human Ubiquitin Journal of Physical Chemistry B 120(33):8313-8320.

65.

Kristoffer Enøe Johansson, Nicolai Tidemand Johansen, Signe Christensen, Scott Horowitz, James C. A. Bardwell, Johan Gotthardt Olsen, Martin Willemoës, Kresten Lindorff-Larsen, Jesper Ferkinghoff-Borg, Thomas Wim Hamelryck and Jakob R. Winther. (2016) Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template Journal of Molecular Biology 428(21):4361-4377.

66.

Michael W. Christiansen, Colette Matthewman, Dagmara Agata Podzimska-Sroka, Charlotte O'Shea, Søren Lindemose, Niels Erik Møllegaard, Inger Bæksted Holme, Kim Hebelstrup, Karen Skriver and Per L. Gregersen. (2016) Barley plants over-expressing the NAC transcription factor gene HvNAC005 show stunting and delay in development combined with early senescence Journal of Experimental Botany 67(17):5259-5273.

67.

Michael May, Karen Skriver and Gert Dandanell. (2016) Towards a cognitive semiotics of science Meaning, mind and communication 67(17):5259-5273.

68.

Nicholas Peter Schafer, Ha H. Truong, Daniel E. Otzen, Kresten Lindorff-Larsen and Peter G. Wolynes. (2016) Topological constraints and modular structure in the folding and functional motions of GlpG, an intramembrane protease Proceedings of the National Academy of Sciences of the United States of America 113(8):2098-2103.

69.

Richard T. Timms, Sam A. Menzies, Iva A. Tchasovnikarova, Lea Cecilie Christensen, James C. Williamson, Robin Antrobus, Gordon Dougan, Lars Ellgaard and Paul J. Lehner. (2016) Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens Nature Communications 7(6):615-638.

70.

Wouter Krogh Boomsma, Sofie Vincents Nielsen, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen and Lars Ellgaard. (2016) Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases PeerJ 4(3):514-527.

71.

Yong Wang, Elena Papaleo and Kresten Lindorff-Larsen. (2016) Mapping transiently formed and sparsely populated conformations on a complex energy landscape eLife 5(24):4424-4451.

2015

72.

Karen Skriver, Gert Dandanell, Jakob Hjorth von Stemann and Michael May. (2015) Udfordringer ved undervisning i enzymer MONA - Matematik- og Naturfagsdidaktik 2015(1):49-65.

73.

Charlotte O'Shea, Mikael Kryger Jensen, Emil G.P. Stender, Birthe Brandt Kragelund, Martin Willemoës and Karen Skriver. (2015) Protein intrinsic disorder in Arabidopsis NAC transcription factors Biochemical Journal 465(2):281-294.

74.

Christian Berg Oehlenschlæger, Monika Nøhr Løvgreen, Eva Reinauer, Emilia Lehtinen, Marie-Louise Lindberg Pind, Pernille Harris, Jan Martinussen and Martin Willemoës. (2015) Bacillus halodurans strain C125 encodes and synthesizes enzymes from both known pathways to form dUMP directly from Cytosine Deoxyribonucleotides Applied and Environmental Microbiology 81(10):3395-3404.

75.

Dagmara Podzimska-Sroka, Charlotte O'Shea, Per L. Gregersen and Karen Skriver. (2015) NAC transcription factors in senescence Plants 4(3):412-448.

76.

Dennis Hansen, Helen Webb, Jonas Willum Nielsen, Pernille Harris, Jakob R. Winther and Martin Willemoës. (2015) Mutational analysis of divalent metal ion binding in the active site of class II a-mannosidase from Sulfolobus solfataricus Biochemistry 54(11):2032-2039.

77.

Emil G. Stender, Charlotte O'Shea and Karen Skriver. (2015) Subgroup-specific intrinsic disorder profiles of arabidopsis NAC transcription factors Plant Signalling & Behavior 10(6):412-448.

78.

Fernando Martin-García, Elena Papaleo, Paulino Gomez-Puertas, Wouter Krogh Boomsma and Kresten Lindorff-Larsen. (2015) Comparing molecular dynamics force fields in the essential subspace PLoS ONE 10(3):6506-6516.

79.

Helena Safavi-Hemami, Joanna Gajewiak, Santhosh Karanth, Samuel D. Robinson, Beatrix Ueberheide, Adam D. Douglass, Amnon Schlegel, Julita S. Imperial, Maren Watkins, Pradip K. Bandyopadhyay, Mark Yandell, Qing Li, Anthony W. Purcell, Raymond S. Norton, Lars Ellgaard and Baldomero M. Olivera. (2015) Specialized insulin is used for chemical warfare by fish-hunting cone snails Proceedings of the National Academy of Sciences of the United States of America 112(6):1743-1748.

80.

Irina Nikolaeva Marinova, Jacob Engelbrecht, Adrian Ewald, Lasse L. Langholm, Christian Henrik Holmberg, Birthe Brandt Kragelund, Colin Gordon, Olaf Nielsen and Rasmus Hartmann-Petersen. (2015) Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing P L o S One 10(2):21141-21153.

81.

Katrine Østergaard Bugge, Helena Steinocher, Andrew J. Brooks, Kresten Lindorff-Larsen and Birthe Brandt Kragelund. (2015) Exploiting hydrophobicity for efficient production of transmembrane helices for structure determination by NMR spectroscopy Analytical Chemistry 87(18):9126–9131.

82.

Kristina Bram Knudsen, Christian Kofoed, Roall Espersen, Casper Højgaard, Jakob R. Winther, Martin Willemoës, Irene Wedin, Markus Nuopponen, Sara Vilske, Kukka Aimonen, Ingrid Elise Konow Weydahl, Harri Alenius, Hannu Norppa, Henrik Wolff, Erik Håkan Richard Wallin and Ulla Vogel. (2015) Visualization of nanofibrillar cellulose in biological tissues using a biotinylated carbohydrate binding module of ß-1,4-Glycanase Chemical Research in Toxicology 28(8):1627-1635.

83.

Lorenzo Sborgi, Abhinav Verma, Stefano Piana, Kresten Lindorff-Larsen, Michele Cerminara, Clara M. Santiveri, David E. Shaw, Eva De Alba and Victor Muñoz. (2015) Interaction networks in protein folding via atomic-resolution experiments and long-time-scale molecular dynamics simulations Journal of the American Chemical Society 137(20):6506-6516.

84.

Matteo Tiberti, Elena Papaleo, Tone Bengtsen, Wouter Krogh Boomsma and Kresten Lindorff-Larsen. (2015) ENCORE PloS Computational Biology 11(10):22–25.

85.

Pengfei Tian, Wouter Krogh Boomsma, Yong Wang, Daniel Otzen, Mogens Høgh Jensen and Kresten Lindorff-Larsen. (2015) Structure of a functional amyloid protein subunit computed using sequence variation Journal of the American Chemical Society 137(1):22–25.

86.

Søs Grønbæk Mathiassen, Ida B. Larsen, Esben Guldahl Poulsen, Christian Toft Madsen, Elena Papaleo, Kresten Lindorff-Larsen, Birthe Brandt Kragelund, Michael Lund Nielsen, Franziska Kriegenburg and Rasmus Hartmann-Petersen. (2015) A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast The Journal of Biological Chemistry 290(34):21141-21153.

2014

87.

Caspar Elo Christensen, Magnus Karlsson, Jakob R. Winther, Pernille Rose Jensen and Mathilde H. Lerche. (2014) Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes The Journal of Biological Chemistry 289(4):2344-2352.

88.

Darrell Cockburn, Casper Wilkens, Christian Ruzanski, Susan Andersen, Jonas Willum Nielsen, Alison M. Smith, Robert A. Field, Martin Willemoës, Maher Abou Hachem and Birte Svensson. (2014) Analysis of surface binding sites (SBSs) in carbohydrate active enzymes with focus on glycoside hydrolase families 13 and 77 - a mini-review Biologia 69(6):705-712.

89.

Elena Papaleo, Ludovico Sutto, Francesco Luigi Gervasio and Kresten Lindorff-Larsen. (2014) Conformational changes and free energies in a Proline isomerase Journal of Chemical Theory and Computation 10(9):4169-4174.

90.

Franziska Kriegenburg, Visnja Jakopec, Esben Guldahl Poulsen, Sofie Vincents Nielsen, Assen Roguev, Nevan Krogan, Colin Gordon, Ursula Fleig and Rasmus Hartmann-Petersen. (2014) A chaperone-assisted degradation pathway targets kinetochore proteins to ensure genome stability P L o S Genetics 10(1):21141-21153.

91.

Gaetano Invernizzi, Matteo Tiberti, Matteo Lambrughi, Kresten Lindorff-Larsen and Elena Papaleo. (2014) Communication routes in ARID domains between distal residues in Helix 5 and the DNA-binding loops P L o S Computational Biology (Online) 10(9):4169-4174.

92.

Henning Gram Hansen, Cecilie Lützen Søltoft, Jonas Damgård Schmidt, Julia Birk, Christian Appenzeller-Herzog and Lars Ellgaard. (2014) Biochemical evidence that regulation of Ero1ß activity in human cells does not involve the isoform-specific cysteine 262 Bioscience Reports 34(2):106-116.

93.

Jakob R. Winther and Colin Thorpe. (2014) Quantification of thiols and disulfides BBA General Subjects 1840(2):838-846.

94.

Jan Halborg Jensen, Martin Willemoës, Jakob R. Winther and Luca De Vico. (2014) In Silico prediction of mutant HIV-1 proteases cleaving a target sequence P L o S One 9(5):281-294.

95.

Konstantinos Paraskevopoulos, Franziska Kriegenburg, Michael H. Tatham, Heike Ilona Rösner, Bethan Medina, Ida B. Larsen, Rikke Brandstrup, Kevin G. Hardwick, Ronald T. Hay, Birthe Brandt Kragelund, Rasmus Hartmann-Petersen and Colin Gordon. (2014) Dss1 is a 26S proteasome ubiquitin receptor Molecular Cell 56(3):453-461.

96.

Kristine Steen Jensen, Jeppe Trudslev Pedersen, Jakob R. Winther and Kaare Teilum. (2014) The pKa value and accessibility of cysteine residues are key determinants for protein substrate discrimination by glutaredoxin Biochemistry 53(15):2533-2540.

97.

Lars Behrendt, Jeppe Lund Nielsen, Søren Johannes Sørensen, Anthony W. D. Larkum, Jakob R. Winther and Michael Kühl. (2014) Rapid TaqMan-based quantification of chlorophyll d-containing cyanobacteria in the genus Acaryochloris Applied and Environmental Microbiology 80(10):3244-3249.

98.

Louise Madsen, Karen Molbæk Hansen, Ida B. Larsen, Sofie V. Nielsen, Esben Guldahl Poulsen, Peter Schledermann Walmod, Kay Hofmann, Michael Seeger, Chen-Ying Chien, Rey-Huei Chen, Franziska Kriegenburg and Rasmus Hartmann-Petersen. (2014) Human ASPL/TUG interacts with p97 and complements the proteasome mislocalization of a yeast ubx4 mutant, but not the ER-associated degradation defect B M C Cell Biology 15(3):453-461.

99.

Michael Henrik Hagemann-Jensen, Franziska Katharina Uhlenbrock, Stephanie Kehlet, Lars Andresen, Charlotte Gabel-Jensen, Lars Ellgaard, Bente Gammelgaard and Søren Skov. (2014) The selenium metabolite methylselenol regulates the expression of ligands that trigger immune activation through the lymphocyte receptor NKG2D The Journal of Biological Chemistry 289(6):31576-31590.

100.

Michael Krogh Jensen and Karen Skriver. (2014) NAC transcription factor gene regulatory and protein-protein interaction networks in plant stress responses and senescence I U B M B Life 66(3):156-166.

101.

Michael Riis Hansen, Eric W. Barr, Kaj Frank Jensen, Martin Willemoës, Charles Grubmeyer and Jakob R. Winther. (2014) Catalytic site interactions in yeast OMP synthase Archives of Biochemistry and Biophysics 542(6):28-38.

102.

Pengfei Tian, Sigurður Ægir Jónsson, Jesper Ferkinghoff-Borg, Sergei V . Krivov, Kresten Lindorff-Larsen, Anders Irbäck and Wouter Krogh Boomsma. (2014) Robust estimation of diffusion-optimized ensembles for enhanced sampling Journal of Chemical Theory and Computation 10(2):543–553.

103.

Simon Olsson, Beat Rolf Vögeli, Andrea Cavalli, Wouter Krogh Boomsma, Jesper Ferkinghoff-Borg, Kresten Lindorff-Larsen and Thomas Wim Hamelryck. (2014) Probabilistic determination of native state ensembles of proteins Journal of Chemical Theory and Computation 10(8):3484-3491.

104.

Søren Lindemose, Michael K. Jensen, Jan Van de Velde, Charlotte O'Shea, Ken S. Heyndrickx, Christopher Workman, Klaas Vandepoele, Karen Skriver and Federico De Masi. (2014) A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana Nucleic Acids Research 42(12):7681-7693.

105.

Thomas Ramming, Henning Gram Hansen, Kazuhiro Nagata, Lars Ellgaard and Christian Appenzeller-Herzog. (2014) GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum Free Radical Biology & Medicine 70(6):106-116.

106.

Wouter Krogh Boomsma, Jesper Ferkinghoff-Borg and Kresten Lindorff-Larsen. (2014) Combining experiments and simulations using the maximum entropy principle PloS Computational Biology 10(2):543–553.

107.

Wouter Krogh Boomsma, Pengfei Tian, Jes Frellsen, Jesper Ferkinghoff-Borg, Thomas Wim Hamelryck, Kresten Lindorff-Larsen and Michele Vendruscolo. (2014) Equilibrium simulations of proteins using molecular fragment replacement and NMR chemical shifts Proceedings of the National Academy of Sciences of the United States of America 111(38):13852-13857.

2013

108.

Anders Steen Christensen, Troels Emtekær Linnet, Mikael Borg, Wouter Krogh Boomsma, Kresten Lindorff-Larsen, Thomas Wim Hamelryck and Jan Halborg Jensen. (2013) Protein structure validation and refinement using amide proton chemical shifts derived from quantum mechanics PLoS ONE 8(12):4169-4174.

109.

Davide Montero, Christine Tachibana, Jakob R. Winther and Christian Appenzeller-Herzog. (2013) Intracellular glutathione pools are heterogeneously concentrated Redox Biology 1(1):508-513.

110.

Jakob R. Winther and Ursula Jakob. (2013) Redox control Nature Chemical Biology 9(2):69-70.

111.

Jean O'Donoghue, Dawadschargal Bech-Otschir, Ida Larsen, Mairi Wallace, Rasmus Hartmann-Petersen and Colin Gordon. (2013) Nedd8 processing enzymes in Schizosaccharomyces pombe B M C Biochemistry 14(8):1-6.

112.

Michael Krogh Jensen, Søren Lindemose, Federico de Masi, Julia J. Reimer, Michael Nielsen, Venura Perera, Chris T. Workman, Franziska Turck, Murray R. Grant, John Mundy, Morten Petersen and Karen Skriver. (2013) ATAF1 transcription factor directly regulates abscisic acid biosynthetic gene NCED3 in Arabidopsis thaliana FEBS Open Bio 3(12):321-327.

113.

Michael May, Karen Skriver and Gert Dandanell. (2013) Technical and didactic problems of virtual lab exercises in biochemistry and biotechnology education False 23(1):81-90.

114.

Naoyuki Umemoto, Takayuki Ohnuma, Mamiko Mizuhara, Hirokazu Sato, Karen Skriver and Tamo Fukamizo. (2013) Introduction of a tryptophan side chain into subsite +1 enhances transglycosylation activity of a GH-18 chitinase from Arabidopsis thaliana, AtChiC Glycobiology 23(1):81-90.

115.

Paola Pietroni, Nishi Vasisht, Jonathan P Cook, David M Roberts, J Michael Lord, Rasmus Hartmann-Petersen, Lynne M Roberts and Robert A Spooner. (2013) The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain Biochemical Journal 453(3):435-445.

116.

Rosa Rebecca Erritzøe Hansen, Mieko Otsu, Ineke Braakman and Jakob R. Winther. (2013) Quantifying changes in the cellular thiol-disulfide status during differentiation of B cells into antibody-secreting plasma cells International Journal of Cell Biology 2013(2):69-70.

117.

Sandro Bottaro, Kresten Lindorff-Larsen and Robert B. Best. (2013) Variational optimization of an all-atom implicit solvent force field to match explicit solvent simulation data Journal of Chemical Theory and Computation 9(12):5641-5652.

118.

Stefano Piana, Kresten Lindorff-Larsen and David E. Shaw. (2013) Atomistic description of the folding of a dimeric protein Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical 117(42):12935-12942.

119.

Søren Lindemose, Charlotte O'Shea, Michael Krogh Jensen and Karen Skriver. (2013) Structure, function and networks of transcription factors involved in abiotic stress responses International Journal of Molecular Sciences (Online) 14(3):5842-78.

120.

Wouter Krogh Boomsma, Jes Frellsen, Tim Philipp Harder, Sandro Bottaro, Kristoffer Enøe Johansson, Pengfei Tian, Kasper Stovgaard, Christian Andreetta, Simon Olsson, Jan Valentin, Lubomir Dimitrov Antonov, Anders Steen Christensen, Mikael Borg, Jan Halborg Jensen, Kresten Lindorff-Larsen, Jesper Ferkinghoff-Borg and Thomas Wim Hamelryck. (2013) PHAISTOS Journal of Computational Chemistry 34(19):1697-1705.

2012

121.

Anna Mosbech, Ian Gibbs-Seymour, Konstantinos Kagias, Tina Thorslund, Petra Beli, Lou Povlsen, Sofie Vincents Nielsen, Stine Smedegaard, Garry Sedgwick, Claudia Lukas, Rasmus Hartmann-Petersen, Jiri Lukas, Chuna Ram Choudhary, Roger David John Pocock, Simon Bekker-Jensen and Niels Mailand. (2012) DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks Nature Structural and Molecular Biology 19(11):1084-92.

122.

Birthe Brandt Kragelund, Michael Krogh Jensen and Karen Skriver. (2012) Order by disorder in plant signaling Trends in Plant Science 17(11):625-632.

123.

Ditte Hededam Welner, Søren Lindemose, J. Günter Grossmann, Niels Erik Møllegaard, Addie Nina Olsen, Charlotte Helgstrand, Karen Skriver and Leila Lo Leggio. (2012) DNA binding by the plant-specific NAC transcription factors in crystal and solution Biochemical Journal 444(1):395-404.

124.

Elena Papaleo, Kresten Lindorff-Larsen and Luca De Gioia. (2012) Paths of long-range communication in the E2 enzymes of family 3 Physical Chemistry Chemical Physics 14(44):12515-12525.

125.

Emily M. Lynes, Michael Bui, Megan C. Yap, Matthew D. Benson, Bobbie Schneider, Lars Ellgaard, Luc G. Berthiaume and Thomas Simmen. (2012) Palmitoylated TMX and calnexin target to the mitochondria-associated membrane E M B O Journal 31(2):457-470.

126.

Esben G Poulsen, Cornelia Steinhauer, Michael Lees, Anne-Marie Lauridsen, Lars Ellgaard and Rasmus Hartmann-Petersen. (2012) HUWE1 and TRIP12 Collaborate in Degradation of Ubiquitin-Fusion Proteins and Misframed Ubiquitin P L o S One 7(11):532-542.

127.

Franziska Kriegenburg, Lars Ellgaard and Rasmus Hartmann-Petersen. (2012) Molecular chaperones in targeting misfolded proteins for ubiquitin-dependent degradation F E B S Journal 279(4):532-542.

128.

Henning Gram Hansen, Jonas Damgård Schmidt, Cecilie Lützen Søltoft, Thomas Ramming, Henrik Marcus Geertz-Hansen, Brian Christensen, Esben Skipper Sørensen, Agnieszka Juncker, Christian Andreas Appenzeller and Lars Ellgaard. (2012) Hyperactivity of the Ero1a oxidase elicits endoplasmic reticulum stress but no broad antioxidant response Journal of Biological Chemistry 287(47):39513-39523.

129.

Jonas Willum Nielsen, Karina Krarup Sand, Christian Schack Pedersen, L. Z. Lakshtanov, Jakob R. Winther, Martin Willemoës and Susan Louise Svane Stipp. (2012) Polysaccharide effects on calcite growth Crystal Growth & Design 12(10):4906-4910.

130.

Jonas Willum Nielsen, Kristine Steen Jensen, Rosa Rebecca Erritzøe Hansen, Charlotte Held Gotfredsen and Jakob R. Winther. (2012) A fluorescent probe which allows highly specific thiol labeling at low pH Analytical Biochemistry 421(1):115-120.

131.

Jonas Willum Nielsen, Nina Rødtness Poulsen, Anna Margit Susanne Johnsson, Jakob R. Winther, Susan Louise Svane Stipp and Martin Willemoës. (2012) Metal-ion dependent catalytic properties of Sulfolobus solfataricus class II a-mannosidase Biochemistry 51(40):8039-8046.

132.

Kresten Lindorff-Larsen, Nikola Trbovic, Paul Maragakis, Stefano Piana and David E Shaw. (2012) Structure and dynamics of an unfolded protein examined by molecular dynamics simulation Journal of the American Chemical Society 134(8):3787-3791.

133.

Kresten Lindorff-Larsen, Paul Maragakis, Stefano Piana, Michael P Eastwood, Ron O Dror and David E Shaw. (2012) Systematic validation of protein force fields against experimental data P L o S One 7(2):5641-5652.

134.

Lea Cecilie Christensen, Njal Winther Jensen, Andrea Lages Lino Vala, Jurate Kamarauskaite, Linda Christina Johansson, Jakob R. Winther, Kay Hofmann, Kaare Teilum and Lars Ellgaard. (2012) The human selenoprotein VCP-interacting membrane protein (VIMP) is non-globular and harbors a reductase function in an intrinsically disordered region Journal of Biological Chemistry 287(31):26388-26399.

135.

Mary Penney, Itaru Samejima, Caroline Wilkinson, Christopher McInerny, Søs Mathiassen, Mairi Wallace, Takashi Toda, Rasmus Hartmann-Petersen and Colin Gordon. (2012) Fission yeast 26S proteasome mutants are multi-drug resistant due to stabilization of the Pap1transcription factor. P L o S One 7(11):1084-92.

136.

Stefano Piana, Kresten Lindorff-Larsen and David E. Shaw. (2012) Protein folding kinetics and thermodynamics from atomistic simulation Proceedings of the National Academy of Sciences of the United States of America 109(44):17845-17850.

137.

Stefano Piana, Kresten Lindorff-Larsen, Robert M Dirks, John K Salmon, Ron O Dror and David E Shaw. (2012) Evaluating the effects of cutoffs and treatment of long-range electrostatics in protein folding simulations P L o S One 7(6):3787-3791.

2011

138.

Jan Martinussen, Martin Willemoës and Mogens Kilstrup. (2011) The Biochemical Basis | Nucleotide Metabolism Comprehensive Biotechnology. 51(40):8039-8046.

139.

Stefano Piana, Krishnarjun Sarkar, Kresten Lindorff-Larsen, Minghao Guo, Martin Gruebele and David E Shaw. (2011) Computational design and experimental testing of the fastest-folding ß-sheet protein Journal of Molecular Biology 405(1):43-48.

140.

Franziska Kriegenburg, Esben G Poulsen, Annett Koch, Elke Krüger and Rasmus Hartmann-Petersen. (2011) Redox control of the ubiquitin-proteasome system Antioxidants & Redox Signaling 15(8):2265-99.

141.

Iben H. Lauritsen, Martin Willemoës, Kaj Frank Jensen, Eva Johansson and Pernille Harris. (2011) Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 67(2):201-208.

142.

Jan Riemer, Henning G Hansen, C. Appenzeller-Herzog, Christian Appenzeller-Herzog, Linda Johansson and Lars Ellgaard. (2011) Identification of the PDI-family member ERp90 as an interaction partner of ERFAD P L o S One 6(2):485-92.

143.

Katrine M Andersen, Camilla Jensen, Franziska Kriegenburg, Anne-Marie B Lauridsen, Colin Gordon and Rasmus Hartmann-Petersen. (2011) Txl1 and Txc1 are co-factors of the 26S proteasome in fission yeast Antioxidants & Redox Signaling 14(9):1601-8.

144.

Kresten Lindorff-Larsen, Stefano Piana, Ron O Dror and David E Shaw. (2011) How fast-folding proteins fold Science (New York, N.Y.) 334(6055):517-20.

145.

Kristine Steen Jensen, Jakob R Winther and Kaare Teilum. (2011) Millisecond dynamics in glutaredoxin during catalytic turnover is dependent on substrate binding and absent in the resting states Journal of the American Chemical Society 133(9):3034-42.

146.

Melanie Kny, Sybille Standera, Rasmus Hartmann-Petersen, Peter-Michael Kloetzel and Michael Seeger. (2011) Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner Journal of Biological Chemistry 286(7):5151-6.

147.

Neil J Bulleid and Lars Ellgaard. (2011) Multiple ways to make disulfides Trends in Biochemical Sciences 36(9):485-92.

148.

Rasmus W. Nielsen, Christine Tachibana, Niels Erik Hansen and Jakob R Winther. (2011) Trisulfides in Proteins Antioxidants & Redox Signaling 15(1):67-75.

149.

Stefano Piana, Kresten Lindorff-Larsen and David E Shaw. (2011) How robust are protein folding simulations with respect to force field parameterization? Biophysical Journal (2011) 100(9):L47-L49.

150.

T. Letzel, E. Sahmel-Schneide, K. Skriver, T. Ohnuma and T. Fukamizo. (2011) Chitinase-catalyzed hydrolysis of 4-nitrophenyl penta-N-acetyl-B-chitopentaoside as determined by real-time ESI-MS Carbohydrate Research 346(6):863-866.

151.

Takayuki Ohnuma, Tomoyuki Numata, Takuo Osawa, Mamiko Mizuhara, Outi Lampela, André H Juffer, Karen Skriver and Tamo Fukamizo. (2011) A class V chitinase from Arabidopsis thaliana: gene responses, enzymatic properties, and crystallographic analysis Planta 234(1):123-37.

152.

Trine Kjaersgaard, Michael K Jensen, Michael W Christiansen, Per L. Gregersen, Birthe B Kragelund and Karen Skriver. (2011) Senescence-associated barley NAC (NAM, ATAF1,2, CUC) transcription factor interacts with radical-induced cell death 1 through a disordered regulatory domain Journal of Biological Chemistry 286(41):35418-29.

2010

153.

Christian Appenzeller-Herzog, Jan Riemer, Ester Zito, King-Tung Chin, David Ron, Martin Spiess and Lars Ellgaard. (2010) Disulphide production by Ero1a-PDI relay is rapid and effectively regulated EMBO Journal 29(19):3318-29.

154.

Kresten Lindorff-Larsen, Stefano Piana, Kim Palmo, Paul Maragakis, John L Klepeis, Ron O Dror and David E Shaw. (2010) Improved side-chain torsion potentials for the Amber ff99SB protein force field Proteins: Structure, Function, and Bioinformatics 78(8):1950-8.

155.

Michael K Jensen, Trine Kjaersgaard, Michael M. Nielsen, Pernille Galberg, Klaus Petersen, Charlotte O'Shea and Karen Skriver. (2010) The Arabidopsis thaliana NAC transcription factor family: structure-function relationships and determinants of ANAC019 stress signalling Biochemical Journal 426(2):183-96.

156.

Bjarne Hove-Jensen, Tina J. Rosenkrantz, David L. Zechel and Martin Willemoës. (2010) Accumulation of intermediates of the carbon-phosphorus lyase pathway for phosphonate degradation in phn mutants of Escherichia coli Journal of Bacteriology 192(1):370-374.

157.

David E Shaw, Paul Maragakis, Kresten Lindorff-Larsen, Stefano Piana, Ron O Dror, Michael P Eastwood, Joseph A Bank, John M Jumper, John K Salmon, Yibing Shan and Willy Wriggers. (2010) Atomic-level characterization of the structural dynamics of proteins Science (New York, N.Y.) 330(6002):341-6.

158.

Doris Roth, Emily Lynes, Jan Riemer, Henning Gram Hansen, Nils Althaus, Thomas Simmen and Lars Ellgaard. (2010) A di-arginine motif contributes to the ER localization of the type I transmembrane ER oxidoreductase TMX4 Biochemical Journal 425(1):195-205.

159.

Franziska Kriegenburg and Rasmus Hartmann-Petersen. (2010) Cdc48 connects with eIF3 Cell Cycle 9(1):22-27.

160.

Kenji Maeda, Per Hägglund, Olof Björnberg, Jakob R Winther and Birte Svensson. (2010) Kinetic and thermodynamic properties of two barley thioredoxin h isozymes, HvTrxh1 and HvTrxh2 FEBS Letters 584(15):3376-3380.

161.

Michael Krogh Jensen, Trine Kjærsgaard, Klaus Petersen and Karen Skriver. (2010) NAC genes: Time-specific regulators of hormonal signaling in Arabidopsis Plant Signalling & Behavior 5(7):183-96.

162.

Morten Ø Jensen, David W Borhani, Kresten Lindorff-Larsen, Paul Maragakis, Vishwanath Jogini, Michael P Eastwood, Ron O Dror and David E Shaw. (2010) Principles of conduction and hydrophobic gating in K+ channels Proceedings of the National Academy of Sciences of the United States of America 107(13):5833-8.

163.

Rasmus Iversen, Peter Anders Andersen, Kristine Steen Jensen, Jakob R. Winther and Bent Walther Sigurskjold. (2010) Thiol-Disulfide Exchange between Glutaredoxin and Glutathione Biochemistry 49(4):810-820.

164.

Rodrigo Cabrera, Zhe Sha, Tegy J. Vadakkan, Joel Otero, Franziska Kriegenburg, Rasmus Hartmann-Petersen, Mary E. Dickinson and Eric C. Chang. (2010) Proteasome nuclear import mediated by Arc3 can influence efficient DNA damage repair and mitosis in Schizosaccharomyces pombe Molecular Biology of the Cell 21(18):3125-3136.

165.

Ryan Chao, Linda Nevin, Pooja Agarwal, Jan Riemer, Xiaoyang Bai, Allen Delaney, Matthew Akana, Nelson JimenezLopez, Tanya Bardakjian, Adele Schneider, Nicolas Chassaing, Daniel F Schorderet, David FitzPatrick, Pui-yan Kwok, Lars Ellgaard, Douglas B Gould, Yan Zhang, Jarema Malicki, Herwig Baier and Anne Slavotinek. (2010) A male with unilateral microphthalmia reveals a role for TMX3 in eye development PLoS ONE 5(5):e10565.

166.

Tuhina Mazumdar, F Murat Gorgun, Youbao Sha, Alexey Tyryshkin, Shenyan Zeng, Rasmus Hartmann-Petersen, Jakob Ploug Jørgensen, Klavs B Hendil and N Tony Eissa. (2010) Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13) Proceedings of the National Academy of Science of the United States of America 107(31):13854-9.

2009

167.

Willy Wriggers, Kate A. Stafford, Yibing Shan, Stefano Piana, Paul Maragakis, Kresten Lindorff-Larsen, Patrick J. Miller, Justin Gullingsrud, Charles A. Rendleman, Michael P. Eastwood, Ron O. Dror and David E. Shaw. (2009) Automated Event Detection and Activity Monitoring in Long Molecular Dynamics Simulations Journal of Chemical Theory and Computation 5(10):2595-2605.

168.

David E. Shaw, Ron O. Dror, John K. Salmon, J. P. Grossman, Kenneth M. Mackenzie, Joseph A. Bank, Cliff Young, Martin M. Deneroff, Brannon Batson, Kevin J. Bowers, Edmond Chow, Michael P. Eastwood, Doug Ierardi, John L. Klepeis, Jeffrey Kuskin, Richard H. Larson, Kresten Lindorff-Larsen, Paul Maragakis, Mark A. Moraes, Stefano Piana, Yibing Shan and Brian Towles. (2009) Millisecond-scale molecular dynamics simulations on Anton Proceedings of the Conference on High Performance Computing Networking, Storage and Analysis 5(10):2595-2605.

169.

Jan Riemer, Christian Appenzeller-Herzog, Linda Johansson, Bernd Bodenmiller, Rasmus Hartmann-Petersen and Lars Ellgaard. (2009) A luminal flavoprotein in endoplasmic reticulum-associated degradation Proceedings of the National Academy of Science of the United States of America 106(35):14831-6.

170.

John L Klepeis, Kresten Lindorff-Larsen, Ron O Dror and David E Shaw. (2009) Long-timescale molecular dynamics simulations of protein structure and function Current Opinion in Structural Biology 19(2):120-7.

171.

Julie H B Siggaard, Eva Johansson, Tina Reinholdt Vognsen, Signe Smedegaard Helt, Pernille Harris, Sine Larsen and Martin Willemoës. (2009) Concerted bifunctionality of the dCTP deaminase-dUTPase from Methanocaldococcus jannaschii: a structural and pre-steady state kinetic analysis Archives of Biochemistry and Biophysics 490(1):42-9.

172.

Katrine M Andersen, Louise Kjær Klausen, Søren Prag, Anders H Johnsen, Colin A Semple, Klavs B Hendil and Rasmus Hartmann-Petersen. (2009) Thioredoxin Txnl1/TRP32 Is a Redox-active Cofactor of the 26 S Proteasome Journal of Biological Chemistry 284(22):15246-15254.

173.

Klaus Aksel Bjørner Hendil, Franziska Kriegenburg, Keiji Tanaka, Shigeo Murata, Anne-Marie B Lauridsen, Anders H Johnsen and Rasmus Hartmann-Petersen. (2009) The 20S proteasome as an assembly platform for the 19S regulatory complex Journal of Molecular Biology 394(2):320-328.

174.

Kresten Lindorff-Larsen and Jesper Ferkinghoff-Borg. (2009) Similarity measures for protein ensembles PLoS ONE 4(1):2595-2605.

175.

Kristine Steen Jensen, Rosa Erritzøe Hansen and Jakob R Winther. (2009) Kinetic and Thermodynamic Aspects of Cellular Thiol-Disulfide Redox Regulation Antioxidants & Redox Signaling 11(5):1047-1058.

176.

Louise Madsen, Michael Seeger, Colin A Semple and Rasmus Hartmann-Petersen. (2009) New ATPase regulators-p97 goes to the PUB International Journal of Biochemistry & Cell Biology 41(12):2380-8.

177.

Nicole Dennhart, Linda M M Weigang, Maho Fujiwara, Tamo Fukamizo, Karen Skriver and Thomas Letzel. (2009) 26kDa endochitinase from barley seeds: real-time monitoring of the enzymatic reaction and substrate binding experiments using electrospray ionization mass spectrometry Journal of Biotechnology 143(4):274-83.

178.

Rosa E Hansen and Jakob R Winther. (2009) An introduction to methods for analyzing thiols and disulfides: Reactions, reagents, and practical considerations Analytical Biochemistry 394(2):147-58.

179.

Rosa E Hansen, Doris Roth and Jakob R Winther. (2009) Quantifying the global cellular thiol-disulfide status Proceedings of the National Academy of Science of the United States of America 106(2):422-427.

180.

Stig Christoffersen, Anders Kadziola, Eva Johansson, Michael Rasmussen, Martin Willemoës and Kaj Frank Jensen. (2009) Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus Journal of Molecular Biology 393(2):464-477.

181.

Tamo Fukamizo, Ryoh Miyake, Atsushi Tamura, Tasayuki Ohnuma, Karen Skriver, Niko Pursiainen and Andre Juffer. (2009) A flexible loop controlling the enzymatic activity and specificity in a glycosyl hydrolase family 19 endochitinase from barley seeds Biochimica et Biophysica Acta - Proteins and Proteomics 1794(8):1159-1167.

2008

182.

Anders B. Nørgaard, Jesper Ferkinghoff-Borg and Kresten Lindorff-Larsen. (2008) Experimental parameterization of an energy function for the simulation of unfolded proteins Biophysical Journal 94(1):182-192.

183.

Christian Appenzeller-Herzog and Lars Ellgaard. (2008) In vivo reduction-oxidation state of protein disulfide isomerase: the two active sites independently occur in the reduced and oxidized forms Antioxidants & Redox Signaling 10(1):55-64.

184.

Christian Appenzeller-Herzog, Jan Riemer, Brian Christensen, Esben B. Sørensen and Lars Ellgaard. (2008) A novel disulphide switch mechanism in Ero1 balances ER oxidation in human cells EMBO Journal 27(35):2977–2987.

185.

Franziska Kriegenburg, Michael Seeger, Yasushi Saeki, Keiji Tanaka, Anne-Marie B Lauridsen, Rasmus Hartmann-Petersen and Klavs B Hendil. (2008) Mammalian 26S proteasomes remain intact during protein degradation Cell 135(2):355-65.

186.

Giuseppe Maulucci, Valentina Labate, Marina Mele, Emiliano Panieri, Giuseppe Arcovito, Tommaso Galeotti, Henrik Østergaard, Jakob R Winther, Marco De Spirito and Giovambattista Pani. (2008) High-resolution imaging of redox signaling in live cells through an oxidation-sensitive yellow fluorescent protein Science signaling 1(43):pl3 1-15.

187.

H Reynaldo López-Mirabal, Jakob R Winther and Morten C Kielland-Brandt. (2008) Oxidant resistance in a yeast mutant deficient in the Sit4 phosphatase Current Genetics 53(5):275-86.

188.

H Reynaldo López-Mirabal, Jakob R Winther, Michael Thorsen and Morten C Kielland-Brandt. (2008) Mutations in the RAM network confer resistance to the thiol oxidant 4,4'-dipyridyl disulfide Molecular Genetics and Genomics 279(6):629-42.

189.

Jakob Wiborg, Charlotte O'Shea and Karen Skriver. (2008) Biochemical function of typical and variant Arabidopsis thaliana U-box E3 ubiquitin-protein ligases Biochemical Journal 413(3):447-457.

190.

Kaj Frank Jensen, Gert Dandanell, Bjarne Hove-Jensen and Martin Willemoës. (2008) Nucleotides, Nucleosides, and Nucleobases EcoSal. Escherichia coli and Salmonella: cellular and molecular biology 490(1):42-9.

191.

Louise Madsen, Katrine M Andersen, Søren Prag, Torben Moos, Colin A Semple, Michael Seeger and Rasmus Hartmann-Petersen. (2008) Ubxd1 is a novel co-factor of the human p97 ATPase. International Journal of Biochemistry & Cell Biology 40(12):2927-42.

192.

M. M. Nielsen, E. S. Seo, A. Dilokpimol, J. Andersen, M. Abou Hachem, H. Naested, Martin Willemoës, S. Bozonnet, L. Kandra, G. Gymnt, R. Haser, N. Aghajari and B. Svensson. (2008) Roles of multiple surface sites, long substrate binding clefts, and carbohydrate binding modules in the action of amylolytic enzymes on polysaccharide substrates Biocatalysis and Biotransformation 26:59-67.

193.

Nadine Anders, Michael M. Nielsen, Jutta Keicher, York-Dieter Stierhof, Masahiko Furutani, Gerd Jürgens, Masao Tasaka and Karen Skriver. (2008) Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains Plant Cell 20(1):142-51.

194.

Paul Maragakis, Kresten Lindorff-Larsen, Michael P Eastwood, Ron O Dror, John L Klepeis, Isaiah T Arkin, Morten Ø Jensen, Huafeng Xu, Nikola Trbovic, Richard A Friesner, Arthur G Palmer Iii and David E Shaw. (2008) Microsecond molecular dynamics simulation shows effect of slow loop dynamics on backbone amide order parameters of proteins Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical 112(19):6155-6158.

195.

Signe Smedegaard Helt, Majbritt Thymark, Pernille Harris, Claus Aagaard, Jes Dietrich, Sine Larsen and Martin Willemoes. (2008) Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis Journal of Molecular Biology 376(2):554-69.

2007

196.

Christian D Geierhaas, Adrian A Nickson, Kresten Lindorff-Larsen, Jane Clarke and Michele Vendruscolo. (2007) BPPred Protein Science 16(1):125-34.

197.

Christian Appenzeller-Herzog and Lars Ellgaard. (2007) The human PDI family: Versatility packed into a single fold. BBA General Subjects 280(46):33859-33867.

198.

Eva Johansson, Majbritt Thymark, Julie H Bynck, Mathias Fanø, Sine Larsen and Martin Willemoës. (2007) Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme FEBS Journal 274(16):4188-4198.

199.

H Reynaldo López-Mirabal and Jakob R Winther. (2007) Redox characteristics of the eukaryotic cytosol. BBA General Subjects 7(3):391-403.

200.

H Reynaldo López-Mirabal and Jakob R Winther. (2007) The thiol oxidant dipyridyl disulfide can supply the PDI-Ero1p pathway with additional oxidative equivalents. Antonie van Leeuwenhoek. International Journal of General and Molecular Microbiology 92(4):463-72.

201.

H Reynaldo López-Mirabal, Jakob R Winther and Morten C Kielland-Brandt. (2007) Genetic interaction between the ero1-1 and leu2 mutations in Saccharomyces cerevisiae. Bioscience, Biotechnology, and Biochemistry 71(12):2934-42.

202.

H Reynaldo López-Mirabal, Michael Thorsen, Morten C Kielland-Brandt, Michel B Toledano and Jakob R Winther. (2007) Cytoplasmic glutathione redox status determines survival upon exposure to the thiol-oxidant 4,4'-dipyridyl disulfide. FEMS Yeast Research 7(3):391-403.

203.

Johannes Haugstetter, Maurer Michael, Thomas Blicher, Martin Pagac, Gerhard Wider and Lars Ellgaard. (2007) Structure-function analysis of the ER oxidoreductase TMX3 reveals interdomain stabilization of the N-terminal redox-active domain Journal of Biological Chemistry 280(46):33859-33867.

204.

Katrine M Andersen, Colin A Semple and Rasmus Hartmann-Petersen. (2007) Characterisation of the nascent polypeptide-associated complex in fission yeast. Molecular Biology Reports 34(4):275-81.

205.

Kristofer Modig, Vibeke W. Jürgensen, Kresten Lindorff-Larsen, Wolfgang Fieber, Henrik G Bohr and Flemming Martin Poulsen. (2007) Detection of initiation sites in protein folding of the four helix bundle ACBP by chemical shift analysis. FEBS Letters 581(25):4965-4971.

206.

Louise Kjær Klausen, Andrea Schulze, Michael Seeger and Rasmus Hartmann-Petersen. (2007) Ubiquitin domain proteins in disease Biochemistry 8(1):1.

207.

Majbritt Thymark, Eva Johansson, Sine Larsen and Martin Willemoës. (2007) Mutational analysis of the nucleotide binding site of Escherichia coli dCTP deaminase Archives of Biochemistry and Biophysics 470(1):20-6.

208.

Mario Schelhaas, Johan Malmström, Lucas Pelkmans, Johannes Haugstetter, Lars Ellgaard, Kay Grünewald and Ari Helenius. (2007) Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells. Cell 131(3):516-29.

209.

Rosa E Hansen, Henrik Østergaard, Per Nørgaard and Jakob R Winther. (2007) Quantification of protein thiols and dithiols in the picomolar range using sodium borohydride and 4,4'-dithiodipyridine. Analytical Biochemistry 363(1):77-82.

210.

Sophie Bozonnet, Morten Tovborg Jensen, Morten Munch Nielsen, Nushin Aghajari, Malene H. Jensen, Birte Kramhøft, Martin Willemoës, Samuel Tanier, Richard Haser and Birte Svensson. (2007) The pair of sugar tongs site on the non-catalytic domain C of barley a-amylase participates in substrate binding and activity FEBS Journal 274(1):5055-5067.

211.

Wenzhong Wang, Jakob R Winther and Colin Thorpe. (2007) Erv2p: characterization of the redox behavior of a yeast sulfhydryl oxidase. Biochemistry 46(11):3246-54.

2006

212.

C. J. Francis, Kresten Lindorff-Larsen, R. B. Best and M. Bendruscolo. (2006) Characterization of the residual structure in the unfolded state of the Delta 131 Delta fragment of staphylococcal nuclease Proteins - Structure Function and Bioinformatics 65(1):145-52.

213.

Heidi Asschenfeldt Ernst, Leila Lo Leggio, M. Willemoes, G. A. Leonard, P. Blum and Sine Larsen. (2006) Structure of the Sulfolobus solfataricus alpha-glucosidase: Implications for domain conservation and substrate recognition in GH31 Journal of Molecular Biology 358(4):1106-24.

214.

Jakob Ploug Jørgensen, Anne-Marie Lauridsen, Poul Kristensen, Karen Dissing, Anders H Johnsen, Klavs B Hendil and Rasmus Hartmann-Petersen. (2006) Adrm1, a putative cell adhesion regulating protein, is a novel proteasome-associated factor. Journal of Molecular Biology 360(5):1043-52.

215.

Kjell Ove Håkansson, Henrik Østergaard and Jakob R. Winther. (2006) Crystallization of mutant forms of glutaredoxin Grx1p from yeast Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 62(9):920-922.

216.

M. ABou Hachem, S. Bozonnet, M. Willemoes, B. Kramhøft, K. Fukuda, Birgit C. Bønsager, M. T. Jensen, J. Nøhr, N. Tranier, N.. Juge, x. Robert, Richard Haser, N. Aghajari and B. Svensson. (2006) Interactions of barley alpha-amylase isozymes with Ca2+, substrates and proteinaceous inhibitors Biocatalysis and Biotransformation 24:83-93.

217.

M. S. Kulp, E. M. Frickel, Lars Ellgaard and J. S. Weismann. (2006) Domain architecture of protein-disulfide isomerase facilitates its dual role as an oxidase and an isomerase in Ero1p-mediated disulfide formation. Journal of Biological Chemistry 281(2):876-84..

218.

M. Louhivuori, R. Otten, Kresten Lindorff-Larsen and A. Annila. (2006) Conformational fluctuations affect protein alignment in dilute liquid crystal media. Journal of the American Chemical Society 128(13):4371-4376.

219.

Maher Abou Hachem, Sophie Bozonnet, Martin Willemoës, Birgit C. Bønsager, Morten Munch Nielsen, Kenji Fukuda, Birte Kramhøft, Kenji Maeda, Bent Walther Sigurskjold, Per Hägglund, Christine Finnie, Haruhide Mori, Xavier Robert, Malene H. Jensen, Samuel Tranier, Nushin Aghajari, Richard Haser and Birte Svensson. (2006) Interactions between Barley a-Amylases, Substrates, Inhibitors and Regulatory Proteins Journal of Applied Glycoscience 53(2):163-169.

220.

Marianne Paulsen, Connie Lund, Zarqa Akram, Jakob R Winther, Nina Horn and Lisbeth Birk Møller. (2006) Evidence that translation reinitiation leads to a partially functional Menkes protein containing two copper-binding sites American Journal of Human Genetics 79(2):214-29.

221.

Michael Nielsen, Jacob Albrethsen, Flemming Hofmann Larsen and K. Skriver. (2006) The Arabidopsis ADP-ribosylation factor (ARF) and ARF-like (ARL) system and its regulation by BIG2, a large ARF-GEF Plant Science 171(6):707-717.

222.

Olof Björnberg, Henrik Ostergaard and Jakob R Winther. (2006) Measuring intracellular redox conditions using GFP-based sensors Antioxidants & Redox Signaling 8:354-61.

223.

Olof Björnberg, Henrik Østergaard and Jakob R Winther. (2006) Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein Biochemistry 45(7):2362-71.

224.

R. B. Best, Kresten Lindorff-Larsen, M. A. DePristo and M. VEndruscolo. (2006) Relation between native ensembles and experimental structures of proteins. Proceedings of the National Academy of Science of the United States of America 103(29):10901-6.

225.

Vidya Chandran, Elliott J Stollar, Kresten Lindorff-Larsen, Jeffrey F Harper, Walter J Chazin, Christopher M Dobson, Ben F Luisi and John Christodoulou. (2006) Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK) Journal of Molecular Biology 357(2):400-10.

2005

226.

Addie Nina Olsen, Heidi Asschenfeldt Ernst, Leila Lo Leggio and Karen Skriver. (2005) DNA-binding specificity and molecular functions of NAC transcription factors Plant Science 169(4):785-797.

227.

Emanuele Paci, K. Lindorff-Larsen, Christopher M. Dobson, Martin Karplus and Michele Vendruscolo. (2005) Transition State Contact Orders Correlate with Protein Folding Rates Journal of Molecular Biology 352(3):495-500.

228.

Eva Johansson, Mathias Fanø, Julie H Bynck, Jan Neuhard, Sine Larsen, Bent W Sigurskjold, Ulla Christensen and Martin Willemoës. (2005) Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes Journal of Biological Chemistry 280(4):3051-9.

229.

Heidi Asschenfeldt Ernst, Martin Willemoës, Leila Lo Leggio, Gordon Leonard, Paul Blum and Sine Larsen. (2005) Characterization of different crystal forms of the a-glucosidase MalA from Sulfolobus solfataricus Acta Crystallographica Section F 61:1039-1042.

230.

Heidi Asschenfeldt Ernst, Martin Willemoës, Leila Lo Leggio, Gordon Leonard, Paul Blum and Sine Larsen. (2005) Characterization of different crystal forms of the alpha-glucosidase MalA from Sulfolobus solfataricus Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 61:1039-42.

231.

Katrine M Andersen, Kay Hofmann and Rasmus Hartmann-Petersen. (2005) Ubiquitin-binding proteins: similar, but different. Essays in Biochemistry 41(5):49-67.

232.

Kresten Lindorff-Larsen, Robert B. Best and Michele Vendruscolo. (2005) Interpreting Dynamically-Averaged Scalar Couplings in Proteins Journal of Biomolecular NMR 32(4):273-280.

233.

Kresten Lindorff-Larsen, Robert B. Best, M. A. DePristo, C. M. Dobson and Michele Vendruscolo. (2005) Simultaneous determination of protein structure and dynamics Nature 433(7022):128-132.

234.

M. M. Dedmon, K. Lindorff-Larsen, J. Christodoulou, Michele Vendruscolo and C. M. Dobson. (2005) Mapping Long-Range Interactions in a-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations Journal of the American Chemical Society 127(2):476-477.

235.

Martin Willemoes and M. Kilstrup. (2005) Nucleoside triphosphate synthesis catalysed by adenylate kinase is ADP dependent Archives of Biochemistry and Biophysics 444(2):195-199.

236.

Rasmus Hartmann-Petersen and Colin Gordon. (2005) Quantifying protein-protein interactions in the ubiquitin pathway by surface plasmon resonance. Methods in Enzymology 399(5):164-77.

237.

Rosa E Hansen, Henrik Østergaard and Jakob R Winther. (2005) Increasing the reactivity of an artificial dithiol-disulfide pair through modification of the electrostatic milieu Biochemistry 44(15):5899-906.

238.

Sophie Bozonnet, Birgit C. Bønsager, Birte Kramhøft, Haruhide Mori, Maher Abou Hachem, Martin Willemoës, Morten T. Jensen, Kenji Fukuda, Peter K. Nielsen, Nathalie Juge, Nushin Aghajari, Samuel Tranier, Xavier Robert, Richard Haser and Birte Svensson. (2005) Binding of carbohydrates and protein inhibitors to the surfaceof a-amylases Biologia 60(16):27-36.

239.

Tsuneo Ohnishi, André H Juffer, Masahiro Tamoi, Karen Skriver and Tamo Fukamizo. (2005) 26 kDa endochitinase from barley seeds: an interaction of the ionizable side chains essential for catalysis Journal of Biochemistry 138(5):553-62.

2004

240.

Jakob R. Winther, Lowri H. Phylip and John Kay. (2004) Saccharopepsin Aspartic and Metallo Peptidases 44(15):5899-906.

241.

Addie Nina Olsen, Heidi Asschenfeldt Ernst, Leila Lo Leggio, Eva Helena Johansson, Sine Larsen and Karen Skriver. (2004) Preliminary crystallographic analysis of the NAC domain of ANAC, a member of the plant-specific NAC transcription factor family Acta Crystallographica. Section D: Biological Crystallography 60(6):112-115.

242.

Camilla Christiansen, Phaedria M St Hilaire and Jakob R. Winther. (2004) Fluorometric polyethyleneglycol-peptide hybrid substrates for quantitative assay of protein disulfide isomerase Analytical Biochemistry 333(1):148-55.

243.

Emanuele Paci, Claire T Friel, Kresten Lindorff-Larsen, Sheena E Radford, Martin Karplus and Michele Vendruscolo. (2004) Comparison of the transition state ensembles for folding of Im7 and Im9 determined using all-atom molecular dynamics simulations with phi value restraints Proteins: Structure, Function, and Bioinformatics 54(3):513-25.

244.

Eva Helena Johansson, Jan Neuhard, Martin Willemoes and Sine Larsen. (2004) Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetramic Cytidine Deaminase Biochemistry 43(16):6020-6029.

245.

Eva Johansson, Jan Neuhard, Martin Willemoës and Sine Larsen. (2004) Structural, kinetic, and mutational studies of the zinc ion environment in tetrameric cytidine deaminase Biochemistry 43(20):6020-9.

246.

Heidi Asschenfeldt Ernst, Addie Nina Olsen, Karen Skriver, Sine Larsen and Leila Lo Leggio. (2004) Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors EMBO Reports 5(4):297-303.

247.

Henrik Østergaard, Christine Tachibana and Jakob R. Winther. (2004) Monitoring disulfide bond formation in the eukaryotic cytosol Journal of Cell Biology 166(3):337-45.

248.

J. Nielsen, M. A. Kristensen, Martin Willemoes, F. C. Nielsen and Jan Christiansen. (2004) Sequential dimerization of human zipcode-binding protein IMP1 on RNA: a cooperative mechanism providing RNP stability Nucleic Acids Research 32(14):4368-4376.

249.

Klavs B Hendil and Rasmus Hartmann-Petersen. (2004) Proteasomes: a complex story. Current Protein and Peptide Science 5(3):135-51.

250.

Kresten Lindorff-Larsen, Michele Vendruscolo, Emanuele Paci and Christopher M Dobson. (2004) Transition states for protein folding have native topologies despite high structural variability Nature Structural and Molecular Biology 11(5):443-9.

251.

Kresten Lindorff-Larsen, Sigridur Kristjansdottir, Kaare Teilum, Wolfgang Fieber, Christopher M Dobson, Flemming Martin Poulsen and Michele Vendruscolo. (2004) Determination of an ensemble of structures representing the denatured state of the bovine acyl-coenzyme a binding protein Journal of the American Chemical Society 126(10):3291-3219.

252.

Martin Willemoes. (2004) Competition between ammonia derived from internal glutamine hydrolysis and hydroxylamine present in the solution for incorporation into UTP as catalysed by Lactococcus lactis CTP synthase Archives of Biochemistry and Biophysics 424(16):105-111.

253.

Miranda Stone, Rasmus Hartmann-Petersen, Michael Seeger, Dawadschargal Bech-Otschir, Mairi Wallace and Colin Gordon. (2004) Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26S proteasome in fission yeast. Journal of Molecular Biology 344(3):697-706.

254.

Pernille Andersen, Birthe B Kragelund, Addie N Olsen, Flemming H Larsen, Nam-Hai Chua, Flemming M Poulsen and Karen Skriver. (2004) Structure and biochemical function of a prototypical Arabidopsis U-box domain Journal of Biological Chemistry 279(38):40053-40061.

255.

Rasmus Hartmann-Petersen and Colin Gordon. (2004) Protein degradation: recognition of ubiquitinylated substrates. Current Biology 14(18):R754-6.

256.

Rasmus Hartmann-Petersen and Colin Gordon. (2004) Integral UBL domain proteins: a family of proteasome interacting proteins. Seminars in Cell and Developmental Biology 15(2):247-59.

257.

Rasmus Hartmann-Petersen, Mairi Wallace, Kay Hofmann, Grete Koch, Anders H Johnsen, Klavs B Hendil and Colin Gordon. (2004) The Ubx2 and Ubx3 cofactors direct Cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes. Current Biology 14(9):824-8.

258.

Rasmus Hartmann-Petersen. (2004) Meeting report: The ubiqitin family gathers The Biochemist 14(26):34-36.

259.

Ruoyu Xiao, Bonney Wilkinson, Anton Solovyov, Jakob R. Winther, Arne Holmgren, Johanna Lundström-Ljung and Hiram F Gilbert. (2004) The contributions of protein disulfide isomerase and its homologues to oxidative protein folding in the yeast endoplasmic reticulum Journal of Biological Chemistry 279(48):49780-6.

260.

Tanja la Cour, Lars Kiemer, Anne Mølgaard, Ramneek Gupta, Karen Skriver and Søren Brunak. (2004) Analysis and prediction of leucine-rich nuclear export signals. Protein Engineering Design and Selection (Print Edition) 17(6):527-36.

2003

261.

Addie Nina Olsen and K. Skriver. (2003) Ligand mimicry? Plant-parasitic nematode polypeptide with similarity to CLAVATA3 Trends in Plant Science 279(8):55-57.

262.

Caroline F Wright, Kresten Lindorff-Larsen, Lucy G Randles and Jane Clarke. (2003) Parallel protein-unfolding pathways revealed and mapped Nature Structural and Molecular Biology 10(8):658-62.

263.

Kresten Lindorff-Larsen, Emanuele Paci, Luis Serrano, Christopher M Dobson and Michele Vendruscolo. (2003) Calculation of mutational free energy changes in transition states for protein folding Biophysical Journal 85(2):1207-14.

264.

Krestine Greve, Tanja La Cour Bravo Munoz, Michael Krogh Jensen, Flemming Martin Poulsen and K. Skriver. (2003) Interactions between plant RING-H2 and plant-specific NAC (NAM/ATAF1/2/CUC2) proteins: RING-H2 molecular specificity and cellular localization. Biochemical Journal 279(371):97-108.

265.

Martin Willemoes and Sine Larsen. (2003) Substrate inhibition of Lactococcus lactis cytidine 5'-triphosphate synthase by ammonium chloride is enhanced by salt-dependent tetramer dissociation Archives of Biochemistry and Biophysics 413(11):17-22.

266.

Martin Willemoes. (2003) Thr-431 and Arg-433 Are Part of a Conserved Sequence Motif of the Glutamine Amidotransferase Domain of CTP Synthases and Are Involved in GTP Activation of the Lactococcus lactis Enzyme Journal of Biological Chemistry 278(11):9407-9411.

267.

Michael Seeger, Rasmus Hartmann-Petersen, Caroline R M Wilkinson, Mairi Wallace, Itaru Samejima, Martin S Taylor and Colin Gordon. (2003) Interaction of the anaphase-promoting complex/cyclosome and proteasome protein complexes with multiubiquitin chain-binding proteins. Journal of Biological Chemistry 278(19):16791-6.

268.

Per Nørgaard, Christine Tachibana, Anette W Bruun and Jakob R. Winther. (2003) Gene regulation in response to protein disulphide isomerase deficiency Yeast (Chichester, England) 20(7):645-52.

269.

Rasmus Hartmann-Petersen, Colin A M Semple, Chris P Ponting, Klavs B Hendil and Colin Gordon. (2003) UBA domain containing proteins in fission yeast. International Journal of Biochemistry & Cell Biology 35(5):629-36.

270.

Rasmus Hartmann-Petersen, Klavs B Hendil and Colin Gordon. (2003) Ubiquitin binding proteins protect ubiquitin conjugates from disassembly. FEBS Letters 535:77-81.

271.

Rasmus Hartmann-Petersen, Michael Seeger and Colin Gordon. (2003) Transferring substrates to the 26S proteasome. TIBS -Trends in Biochemical Sciences. Regular ed. 28(1):26-31.

272.

Tanja La Cour Bravo Munoz, R. Gupta, K. Rapacki, K. Skriver, Flemming Martin Poulsen and S. Brunak. (2003) NESbase version 1.0: a database of nuclear export signals. Nucleic Acids Research 279(31):1393-1396.

2002

273.

Addie Nina Olsen, John Mundy and Karen Skriver. (2002) Peptomics, identification of novel cationic Arabidopsis peptides with conserved sequence motifs. In Silico Biology 2(4):441-51.

274.

Klavs B Hendil, Rasmus Hartmann-Petersen and Keiji Tanaka. (2002) 26 S proteasomes function as stable entities. Journal of Molecular Biology 315(4):627-36.

275.

Martin Willemoes and Bent Walther Sigurskjold. (2002) Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis. The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis FEBS Journal 269(11):4772-4779.

276.

Martin Willemoës, Mogens Kilstrup, Peter Roepstorff and Karin Hammer. (2002) Proteome analysis of a Lactococcus lactis strain overexpressing gapA suggests that the gene product is an auxiliary glyceraldehyde 3-phosphate dehydrogenase Proteomics 2(8):1041-1046.

277.

Søren Prag, Eugene A Lepekhin, Kateryna Kolkova, Rasmus Hartmann-Petersen, Anna Kawa, Peter S Walmod, Vadym Belman, Helen C Gallagher, Vladimir Berezin, Elisabeth Bock and Nina Pedersen. (2002) NCAM regulates cell motility. Journal of Cell Science 115:283-92.

2001

278.

C R Wilkinson, M Seeger, R Hartmann-Petersen, M Stone, M Wallace, C Semple and C Gordon. (2001) Proteins containing the UBA domain are able to bind to multi-ubiquitin chains. Nature Cell Biology 3(10):939-43.

279.

K Møller, L D Tidemand, Jakob R. Winther, Lisbeth Olsson, Jure Piskur and J Nielsen. (2001) Production of a heterologous proteinase A by Saccharomyces kluyveri Applied Microbiology and Biotechnology 57:216-9.

280.

Kresten Lindorff-Larsen and J R Winther. (2001) Surprisingly high stability of barley lipid transfer protein, LTP1, towards denaturant, heat and proteases F E B S Letters 488(3):145-8.

281.

Kresten Lindorff-Larsen, Mathilde H. Lerche, Flemming Martin Poulsen, Peter Roepstorff and Jakob R. Winther. (2001) Barley lipid transfer protein, LTP1, contains a new type of lipid-like post-translational modification Journal of Biological Chemistry 276(36):33547-53.

282.

P S Walmod, R Hartmann-Petersen, A Berezin, S Prag, V V Kiselyov, V Berezin and E Bock. (2001) Evaluation of individual-cell motility. Methods in Molecular Biology 161:59-83.

283.

P Nørgaard, V Westphal, C Tachibana, L Alsøe, B Holst and Jakob R. Winther. (2001) Functional differences in yeast protein disulfide isomerases Journal of Cell Biology 152(3):553-62.

284.

Per Nørgaard and Jakob R. Winther. (2001) Mutation of yeast Eug1p CXXS active sites to CXXC results in a dramatic increase in protein disulphide isomerase activity Biochemical Journal 358(1):269-274.

285.

R Hartmann-Petersen, K Tanaka and K B Hendil. (2001) Quaternary structure of the ATPase complex of human 26S proteasomes determined by chemical cross-linking. Archives of Biochemistry and Biophysics 386(1):89-94.

286.

Rikke B. Jensen, Tanja la Cour, Jacob Albrethsen, Michael Marinus Nielsen and Karen Skriver. (2001) FYVE zinc-finger proteins in the plant model Arabidopsis thaliana: idenfication of Ptdins3P-binding residues by comparison of classic and variant FYVE dominans. Biochemical Journal 2(359):165-173.

287.

Steen L.L. Wadskov-Hansen, Martin Willemoes, Jan Martinussen, Karin Hammer, Jan Neuhard and Sine Larsen. (2001) Cloning and Verification of the Lactococcus lactis pyrG Gene and Characterization of th Gene Product, CTP Synthase Journal of Biological Chemistry 276(8):38002-38009.

2000

288.

Kresten Lindorff-Larsen and Jakob R. Winther. (2000) Thiol alkylation below neutral pH Analytical Biochemistry 286(2):308-10.

289.

M Li, L H Phylip, W E Lees, Jakob R. Winther, B M Dunn, A Wlodawer, J Kay and A Gustchina. (2000) The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix Nature Structural and Molecular Biology 7(2):113-7.

290.

Martin Willemoes, Bjarne Hove-Jensen and Sine Larsen. (2000) Steady State Kinetic Model for the Binding of Substrates and Allosteric Effectors to Escherichia coli Phosphoribosyl-diphosphate Synthase. Journal of Biological Chemistry 45(8):35408-35412.

291.

R B Jensen, K Lykke-Andersen, G I Frandsen, J Haseloff, H M Jespersen, J Mundy and K Skriver. (2000) Promiscuous and specific phospholipid binding by domains in ZAC, a membrane-associated Arabidopsis protein with an ARF GAP zinc finger and a C2 domain. Plant Molecular Biology 44(6):799-814.

292.

R Hartmann-Petersen, P S Walmod, A Berezin, V Berezin and E Bock. (2000) Individual cell motility studied by time-lapse video recording: influence of experimental conditions. Cytometry. Part B: Clinical Cytometry 40(4):260-70.

1999

293.

M U Jørgensen, S D Emr and Jakob R. Winther. (1999) Ligand recognition and domain structure of Vps10p, a vacuolar protein sorting receptor in Saccharomyces cerevisiae European Journal of Biochemistry 260(2):461-9.

294.

Rikke Jensen, Karen Skriver and Hans Jespersen. (1999) PMZ, a cDNA from Arabidopsis thaliana encoding a putative novel zinc finger motif with homologs in vertabrates and mammals Plant Molecular Biology 40(6):745.

295.

V Westphal, N J Darby and Jakob R. Winther. (1999) Functional properties of the two redox-active sites in yeast protein disulphide isomerase in vitro and in vivo Journal of Molecular Biology 286(4):1229-39.

1998

296.

A W Bruun, I Svendsen, S O Sørensen, Morten Kielland-Brandt and Jakob R. Winther. (1998) A high-affinity inhibitor of yeast carboxypeptidase Y is encoded by TFS1 and shows homology to a family of lipid binding proteins Biochemistry 37(10):3351-7.

297.

Dora Raventos Segura, K. Skriver, M. Schlein, K. Karnahl, S. Rogers, J.C. Rogers and John Williams Mundy. (1998) HRT, a novel transcriptional repressor from plants Journal of Biological Chemistry 40(273):23313-20.

298.

J C Spetzler, V Westphal, Jakob R. Winther and M Meldal. (1998) Preparation of fluorescence quenched libraries containing interchain disulphide bonds for studies of protein disulphide isomerases Journal of Peptide Science 4(2):128-37.

299.

T E Maar, Trine Meldgaard Lund, G Gegelashvili, R Hartmann-Petersen, Michael J. Moran, H Pasantes-Morales, V Berezin, E Bock and A Schousboe. (1998) Effects of taurine depletion on cell migration and NCAM expression in cultures of dissociated mouse cerebellum and N2A cells Amino Acids 15(1):77-88.

300.

V Westphal, J C Spetzler, M Meldal, U Christensen and Jakob R. Winther. (1998) Kinetic analysis of the mechanism and specificity of protein-disulfide isomerase using fluorescence-quenched peptides Journal of Biological Chemistry 273(39):24992-9.

1997

301.

Bjørn Holst, Christine Tachibana and Jakob R. Winther. (1997) Active site mutations in yeast protein disulfide isomerase cause dithiothreitol sensitivity and a reduced rate of protein folding in the endoplasmic reticulum Journal of Cell Biology 138(6):1229-1238.

302.

H Van Den Hazel, A M Wolff, Morten Kielland-Brandt and Jakob R. Winther. (1997) Mechanism and ion-dependence of in vitro autoactivation of yeast proteinase A Biochemical Journal(39):339-44.

303.

Martin Willemoës and Bjarne Hove-Jensen. (1997) Binding of Divalent Magnesium by Escherichia coli Phosphoribosyl Diphosphate Synthetase Biochemistry 36(16):5078-5083.

1996

304.

B Holst, A W Bruun, Morten Kielland-Brandt and Jakob R. Winther. (1996) Competition between folding and glycosylation in the endoplasmic reticulum E M B O Journal 15(14):3538-46.

305.

C Ramos and Jakob R. Winther. (1996) Exchange of regions of the carboxypeptidase Y propeptide. Sequence specificity and function in folding in vivo European Journal of Biochemistry 242(1):29-35.

306.

F van Voorst, Morten Kielland-Brandt and Jakob R. Winther. (1996) Mutational analysis of the vacuolar sorting signal of procarboxypeptidase Y in yeast shows a low requirement for sequence conservation Journal of Biological Chemistry 271(2):841-6.

307.

Gitte Frandsen, Frieder Muller-Uri, Michael Nielsen, John Mundy and Karen Skriver. (1996) Novel plant Ca2+-binding protein expressed in response to abscisic acid and osmotic stress The Journal of Biological Chemistry 271(273):343-348.

308.

H B Van Den Hazel, Morten Kielland-Brandt and Jakob R. Winther. (1996) Review Yeast (Chichester, England) 12(1):1-16.

309.

Martin Willemoës, Dan Nilsson and Bjarne Hove-Jensen. (1996) Effects of mutagenesis of aspartic acid residues in the putative phosphoribosyl diphosphate binding site of Escherichia coli phosphoribosyl diphosphate synthetase on metal ion specificity and ribose-5-phosphate binding Biochemistry 35(25):8181-8186.

310.

V Westphal, E G Marcusson, Jakob R. Winther, S D Emr and H B van den Hazel. (1996) Multiple pathways for vacuolar sorting of yeast proteinase A Journal of Biological Chemistry 271(20):11865-70.

1995

311.

H B van den Hazel, Morten Kielland-Brandt and Jakob R. Winther. (1995) Random substitution of large parts of the propeptide of yeast proteinase A Journal of Biological Chemistry 270(15):8602-9.

312.

U Grauschopf, Jakob R. Winther, P Korber, T Zander, P Dallinger and J C Bardwell. (1995) Why is DsbA such an oxidizing disulfide catalyst? Cell 83(6):947-55.

1994

313.

Bushra Chaudhry, Frieder Müller-Uri, Verena Cameron-Mills, Simon Gough, David Simpson, K. Skriver and John Williams Mundy. (1994) The barley 60 kDa jasmonate-induced protein (JIP60) is a novel ribosome-inactivating protein Plant Journal 271:815-824.

314.

C Ramos, Jakob R. Winther and Morten Kielland-Brandt. (1994) Requirement of the propeptide for in vivo formation of active yeast carboxypeptidase Y Journal of Biological Chemistry 269(9):7006-12.

315.

Jakob R. Winther, P Sørensen and Morten Kielland-Brandt. (1994) Refolding of a carboxypeptidase Y folding intermediate in vitro by low-affinity binding of the proregion Journal of Biological Chemistry 269(35):22007-13.

316.

Robert Leah, K. Skriver, Søren Knudsen, Jan Ruud-Hansen, Natasha V. Raikhei and John Williams Mundy. (1994) Identification of an enhancer/silencer sequence directing the aleurone-specific expression of a barley chitinase gene Plant Journal 271:579-589.

317.

S O Sørensen, H B van den Hazel, Morten Kielland-Brandt and Jakob R. Winther. (1994) pH-dependent processing of yeast procarboxypeptidase Y by proteinase A in vivo and in vitro European Journal of Biochemistry 220(1):19-27.

1993

318.

H B van den Hazel, Morten Kielland-Brandt and Jakob R. Winther. (1993) The propeptide is required for in vivo formation of stable active yeast proteinase A and can function even when not covalently linked to the mature region Journal of Biological Chemistry 268(24):18002-7.

319.

P Sørensen, Jakob R. Winther, N C Kaarsholm and F M Poulsen. (1993) The pro region required for folding of carboxypeptidase Y is a partially folded domain with little regular structural core Biochemistry 32(45):12160-6.

1992

320.

H B van den Hazel, Morten Kielland-Brandt and Jakob R. Winther. (1992) Autoactivation of proteinase A initiates activation of yeast vacuolar zymogens European Journal of Biochemistry 207(1):277-83.

1991

321.

Jakob R. Winther and P Sørensen. (1991) Propeptide of carboxypeptidase Y provides a chaperone-like function as well as inhibition of the enzymatic activity Proceedings of the National Academy of Sciences of the United States of America 88(20):9330-4.

322.

Jakob R. Winther, T H Stevens and Morten Kielland-Brandt. (1991) Yeast carboxypeptidase Y requires glycosylation for efficient intracellular transport, but not for vacuolar sorting, in vivo stability, or activity European Journal of Biochemistry 197(3):681-9.

1990

323.

L A Valls, Jakob R. Winther and T H Stevens. (1990) Yeast carboxypeptidase Y vacuolar targeting signal is defined by four propeptide amino acids Journal of Cell Biology 111(2):361-8.

1987

324.

JR WINTHER, K BREDDAM and Jakob R. Winther. (1987) THE FREE SULFHYDRYL-GROUP (CYS341) OF CARBOXYPEPTIDASE-Y - FUNCTIONAL-EFFECTS OF MUTATIONAL SUBSTITUTIONS Carlsberg Research Communications 52(4):263-273.

1986

325.

Lene M. Bech, John Nielsen, Jakob R. Winther, Morten C. Kielland-Brandt and Klaus Breddam. (1986) Mutational replacement of methionine by arginine in the S'1 substrate binding site of yeast carboxypeptidase Carlsberg Research Communications 51(6):459-465.

1985

326.

Jakob R. Winther, Morten C. Kielland-Brandt and Klaus Breddam. (1985) Increased hydrophobicity of the S'1 binding site in carboxypeptidase Y obtained by site-directed mutagenesis Carlsberg Research Communications 50(5):273-284.

327.

JR WINTHER, MC KIELLANDBRANDT, K BREDDAM and Jakob R. Winther. (1985) INCREASED HYDROPHOBICITY OF THE S1' BINDING-SITE IN CARBOXYPEPTIDASE-Y OBTAINED BY SITE-DIRECTED MUTAGENESIS Carlsberg Research Communications 50(5):273-284.

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